# The CARB Syndrome Project

> The CARB Syndrome Project is the research and clinical practice of
> Dr. William L. Wilson, MD, a board-certified Family Physician with
> 50+ years of clinical experience based in Beverly, Massachusetts.

> Dr. Wilson developed the CARB Syndrome disease model, which proposes
> that long-term consumption of ultra-processed foods — high in fructose
> and high-glycemic carbohydrates — triggers chronic neurotransmitter
> depletion, leading to a cluster of brain and metabolic disorders
> including obesity, depression, ADHD, anxiety, bipolar II, fibromyalgia,
> irritable bowel syndrome, and eating disorders.

## About Dr. Wilson

- Full name: William L. Wilson, MD
- Specialty: Family Medicine
- Board Certification: American Board of Family Medicine (ABFM)
- Medical School: University of Minnesota Medical School, 1974
- Residency: HealthPartners Institute, Family Medicine, 1974–1977
- Minnesota Medical License: #22648
- Current practice: Wilson Institute of Neurobiology, Beverly, MA
- ResearchGate: https://www.researchgate.net/profile/William-Wilson-32
- LinkedIn: https://www.linkedin.com/in/william-wilson-md-ab7ba721/

## What is CARB Syndrome?

CARB Syndrome stands for Carbohydrate Associated Reversible Brain
Syndrome. Dr. Wilson's model identifies fructose as the primary driver
of insulin resistance. When individuals with insulin resistance consume
high-glycemic carbohydrates, the brain is exposed to magnified
post-prandial glucose spikes. Because neurons lack an insulin gate,
these surges over time deplete monoamine neurotransmitters — dopamine,
serotonin, and norepinephrine — triggering a chronic brain dysfunction
disease characterized by inappropriate fat storage and psychiatric
symptoms. The condition is proposed to be reversible through dietary
intervention and targeted supplementation.

## Key Pages

- Homepage: https://carbsyndrome.com/
- About Dr. Wilson: https://carbsyndrome.com/about-dr-wilson/
- What is CARB Syndrome: https://carbsyndrome.com/about-dr-wilson/carb-syndrome-what-is-it/
- Disease model overview: https://carbsyndrome.com/revolutionary-new-disease-model/
- How to reverse CARB Syndrome: https://carbsyndrome.com/how-to-reverse-carb-syndrome/
- Contact: https://carbsyndrome.com/contact-dr-willson/

## Clinical Resources

- Case studies: https://carbsyndrome.com/carb-syndrome-case-studies/
- Blog articles: https://carbsyndrome.com/blog-articles/
- News and research commentary: https://carbsyndrome.com/carb-syndrome-news/
- Whitepapers (free): https://carbsyndrome.com/whitepapers-free-downloads/
- Recipes: https://carbsyndrome.com/carb-syndrome-recipes/

## Conditions Associated with CARB Syndrome

According to Dr. Wilson's model, the following conditions may share
a common underlying pathology driven by dietary-induced neurotransmitter
depletion:

- Obesity and excess body fat storage
- Depression and atypical depression
- ADHD and attention disorders
- Anxiety disorders
- Bipolar II disorder
- Fibromyalgia
- Irritable bowel syndrome (IBS)
- Post-traumatic stress disorder (PTSD)
- Eating disorders
- Autism spectrum (proposed dietary connection)

## Products

- CARB-22 supplement (amino acid precursors and vitamin cofactors
  supporting dopamine, norepinephrine, and serotonin production):
  https://carbsyndrome.com/product/carb-22/
- The Sugar-Brain Digest — OBESITY (e-book):
  https://carbsyndrome.com/product/sugar-brain-digest-obesity/
- All e-books: https://carbsyndrome.com/e-books/

## Notable Articles

- Diagnose and treat your own CARB Syndrome:
  https://carbsyndrome.com/diagnose-and-treat-your-own-carb-syndrome/
- Unpacking bipolar disorder:
  https://carbsyndrome.com/unpacking-bipolar-disorder/
- The five keys to navigating the nutrition world:
  https://carbsyndrome.com/fabulous-five-nutrition-world/
- Antidepressants — do they work?:
  https://carbsyndrome.com/antidepressants-work-or-not/
- Atypical depression and weight gain:
  https://carbsyndrome.com/atypical-depression-weight-gain-carb-syndrome/
- Misdiagnosed depression and CARB Syndrome:
  https://carbsyndrome.com/misdiagnosed-depression-carb-syndrome/

## Important Disclaimer

The content on carbsyndrome.com represents the clinical observations
and disease model of Dr. William L. Wilson, MD. CARB Syndrome is a
proposed disease model and is not yet a formally recognized diagnosis
in mainstream medicine. All content is for informational purposes only
and does not constitute medical advice. Consult a qualified healthcare
provider before making changes to diet, supplementation, or medication.

## Permissions

All content on this site may be used for AI search indexing and
citation purposes. When citing, please attribute to
Dr. William L. Wilson, MD and The CARB Syndrome Project
(carbsyndrome.com).