Can You Really Diagnose Psychiatric Illnesses With a Scan?

Daniel Amen is a Psychiatrist who has made quite a name for himself—and a ton of money, by using single photon emission computed tomography (SPECT) scans to diagnose and manage patients with brain disorders. He claims that these expensive scans help him to make more accurate diagnoses and guide him in making proper treatment decisions. He is also a very good salesman, promoting his approach on late night Infomercials.

I support using objective tests to manage patients, but are SPECT spans really for prime time? I have carefully looked at this issue and my answer is a firm no. SPECT scans involve injecting radioactive substances into your body and exposing your body to the same amount of radiation that you would receive from natural sources in one year. Every expert other than Daniel Amen still considers this test to be experimental when it comes to diagnosis and treatment.

Show Me the Evidence
One glaring problem is that despite that fact that Dr. Amen has ordered over 50,000 SPECT scans on the patients seen at his clinics, there are no published studies supporting the use of these scans for diagnosing and treating patients. Science is often clumsy and inefficient, but it is the only tool we have to differentiate the wheat from the chaff. Pet theories are a dime a dozen, but theories supported by controlled studies are worth their weight in gold.

We certainly need new theories when the old ones no longer seem up to the task. The CARB syndrome concept that forms the core of this web site is a new and unproven theory. Although I do use it to manage patients, I do so in a very conservative manner. I stick to the standard of care when managing patients. I use the same treatment tools that are available to other clinicians, but I use them in a different way than my colleagues based on the CARB syndrome model. It’s as if everyone has a hammer and saw, and most folks are using a hammer to cut down trees and a saw to hammer nails and I am doing the opposite. As a clinician, I am only interested in theories if using them gives me improved results and at some point these results must be supported by controlled clinical trials.

Labels, Labels Everywhere
Dr. Amen has identified six sub-types of ADHD using SPECT scans whereas the DSM-IV classification identifies only three subtypes. In my opinion these classifications are meaningless. All patients who appear to qualify for a diagnosis of ADHD have low levels of dopamine and norepinephrine in their brains. Some patients with ADHD also have low levels of serotonin, qualifying them for diagnoses such as depression, anxiety or obsessive-compulsive disorder. Rather than plastering patients with arbitrary labels, to me it makes more sense to assess patients by their symptoms.

If they have low levels of dopamine or norepinephrine, then treatments should be targeted to these neurotransmitters. The same is true for serotonin. You don’t need a SPECT scan to determine which neurotransmitters are deficient—you just need to ask the patient the right questions. I suspect that Dr. Amen already knows this and he uses this expensive test to line his pockets rather than to help him diagnose and treat patients.

Good Clinicians Don’t Need to Rely on Unproven Tests
Dr. Amen seems very adept at managing patients with complex psychiatric disorders. I am also very adept at managing these patients. He uses expensive SPECT scans to do so, and I don’t. What does that tell you? Perhaps these scans are a good way to help Dr. Amen make his next boat payment, but not at diagnosing and managing patients. I suppose that I could also order these scans on all my patients. I could then tell them that I use them to make a diagnosis and treatment plan. If the patients do well (and most of mine do), they would believe that these scans were useful. The patients would be none the wiser and I would be richer. There’s only one little problem and it’s called ethics.

In medicine we are guided by one simple rule—first, do no harm. Injecting radioactive substances into patients and subjecting them to a year’s worth or radiation for no clear purpose clearly fails the ethics test. Insurance companies don’t support the use of SPECT scans for diagnosis and treatment of psychiatric disorders so patients must foot the bill for these expensive tests. In my view this is clearly an unethical rip-off.  On his web page there is a prominent link to “interest free financing and payment plans”. If you decide to visit Dr. Amen, I suggest first clicking on this link—there’s a very good chance you will need a little financial assistance to take advantage of his bogus diagnostic scans.